How Addiction Affects the Brain

First things first: understanding what drives addiction is not generally enough to beat it. However – an understanding of the way addiction hijacks the brain can help to explain why so many people who want to quit find themselves totally powerless.

Cognitive researchers have made huge progress in recent years that has led to a much deeper understanding of what underlies the addictive processes. When researchers first began studying addiction, many believed that worked that people struggling with addiction lacked will power, or didn’t really “want” to stop. Thankfully, researchers have debunked this myth and demonstrated that addiction is a complex, chronic affliction that changes both brain structure and chemistry. Scientists have also recently uncovered that addictions come in many forms; recent government data shows 1 in 10 Americans are addicted to something—from drinking and drugs to food, sex, gambling, or any number of compulsive behaviors.

The Basis of Addiction

The word addiction comes from the Latin term for “enslaved” or “devoted” and anyone who has been affected by addiction—their own or someone else’s— will get this.

Addiction has a powerful impact on the brain. It shows up in a few key ways: craving for the substance or object of addiction, loss of control over its use, and continued use despite negative consequences. Although addiction can be beaten, it takes time and usually requires outside help.

Just as diabetes impairs the pancreas and lung cancer debilitates the lungs, addiction hijacks the brain. Most drugs affect the brain’s reward circuit by flooding it with the chemical dopamine. Dopamine is a neurotransmitter that helps control the brain’s reward and pleasure centers. Surges of dopamine reinforce the enjoyable but unhealthy activity, leading people to repeat the associated behavior again and again, even when returns are diminishing. This process helps explain the addicts’ experience of continuing to go back for more, even though the high is unreliable and the consequences are deadly.

In nature, rewards usually come only with time and effort. Addictive drugs offer a shortcut, flooding the brain with dopamine and other feel-good chemicals. The hippocampus lays down memories of this quick satisfaction, and the amygdala creates a conditioned response to the stimuli.

According to researchers at Harvard Medical School, addictive drugs can release 2 to 10 times the amount of dopamine that natural rewards do, and they do it more quickly and more reliably. The drugs that we think of as particularly “addictive,” like nicotine and opioids, for example, cause a particularly strong surge of dopamine. In the drug addict’s brain, pleasure receptors eventually become overwhelmed. Over time, the brain adapts and produces less dopamine, and drugs no longer deliver the pleasure they once did. Drug users have to take larger amounts to obtain the same dopamine “high” because their brains have essentially re-wired themselves.

At this point, the compulsion usually takes over. Although the high associated with a particular drug or behavior diminishes, the memory of the desired effect and the desire to recreate it continues.

Cravings, both physical and psychological, contribute not only to addiction but also relapse after hard-won sobriety. This inner conditioning and desire for instant pleasure can lead to relapse even after years of abstinence.

There is a Way Out

Without a doubt, the science is supported by the experience of millions of people who’ve repeatedly tried to quit without success. The good news is that millions of others have found a way out. Freedom from addiction is totally possible, although not easy and sometimes downright brutal. Thankfully, help is available. You don’t have to go it alone, and can benefit from the experience of good people who have found a way out.

If you or someone you know is struggling, get in touch. Scottsdale Providence is a leader in results-driven, evidence-based treatment, and our team has decades of experience in helping people find their way out.


It’s not the end. It’s the beginning.

Benefits of EMDR Everything You Need to Know About EMDR what is an addict What is an Addict? overdose rates Twin Pandemics: Overdoses are More Common and Deadly than Ever Before neurofeedback Who is Neurofeedback best suited for? Neurofeedback What are some benefits of Neurofeedback? neurofeedback What is Neurofeedback? What are the Benefits of Somatic Experiencing? How Does Somatic Experiencing Work? Treatment Modalities: What is Somatic Experiencing? overdoses Record Setting Overdose Rates as Pandemic Continues Life After Treatment: Finding Wellness Hope is Alive in Hopelessness scottsdale rehab The Role of Trauma in Addiction Treatment 4 Ways to Stay Sane During COVID-19 mental illness SPRC Primary Mental Health Care The Hidden Epidemic: Coronavirus Pandemic Unleashes a Spike in Overdose Deaths treatment Why Now is the Time to Put Wellness First Social distancing Staying Connected While Social Distancing Treatment Don’t Let Anything Stand in the Way of Change Stress Test: Dealing With Anxiety in Recovery Addiction and the brain How Addiction Affects the Brain OD Overdose Deaths Have Dropped But Remain Shockingly High New Years Resolution 3 Ways to Live Your Best Life in 2020 Does rehab work Does Rehab Work? gratitude The Science of Gratitude Autumn Anxiety is Real: Four Ways to Deal overdoses Overdose Deaths Drop for the First Time Since 1990; Fentanyl Remains Deadly Risk leaving treatment Life After Treatment: Getting Connected and Getting out There sober summer fun 5 Ways To Have Fun in the Sun Without Drinking 12 step spirituality The 12 Steps and the Non-Believer sponsorship The Priceless Magic of Sponsorship 12 Step Fellowship The Undeniable Power of Connection Amends Recovery Thoughts on Amends and Forgiveness New year How to Make 2019 Your Best Year Yet Choosing the Right Treatment Center: 10 Things to Ask Holidays 5 Ways to Stay Sane And Sober Through the Holidays mindfulness A Beginner’s Guide to Mindfulness fentanyl The Problem on the Street: Fentanyl and The New Face of the Opioid Crisis EMDR The Healing Power of EMDR: 2 Women Share Their Experiences Finding Peace at Last: How Neurofeedback Therapy Helped Samantha Get the Help She Needed DBT Healing Through DBT: The Life-Changing Effects of Dialectical Behavioral Therapy CBT How Cognitive Behavioral Therapy Changed Cherie’s Life - and It Can Change Yours, Too recovery month How We Are Celebrating National Recovery Month Overdose Overdose Stats for 2017 Are In: Drug Deaths Are Breaking Records Pay the Bills and More While Getting Your Life on Track Post-Addiction Hope For the Hopeless: Can You Get Sober if You Don't Believe in God? Why Now? Getting Sober Young The First Day of Treatment